Alcohol Addiction: A Molecular Biology Perspective
نویسندگان
چکیده
منابع مشابه
Molecular and Cellular Genetics of Alcohol Addiction
Worldwide, in societies where moderate alcohol consumption is accepted as a pleasurable pastime and even an enhancer of health and well-being, it has historically been observed that a sizable minority is unable to keep within safe limits of consumption. Such individuals may abuse alcohol or become dependent. Alcoholism is today among the most pervasive psychiatric disorders. In the United State...
متن کاملMolecular and Cellular Biology of Addiction
Addiction to alcohol, tobacco, and illegal drugs represents a substantial burden to societies worldwide. In terms of health-related outcomes, addiction results in enormous direct medical costs, premature mortality (tobacco alone may be responsible for 450,000 deaths yearly in the United States), and disability. In terms of broader social costs, addiction results in crime, negative impacts on fa...
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Alcohol dependence, and the medical conditions which arise from prolonged excessive alcohol use, have no single cause. Like other complex diseases, they result from a combination of social, personal and genetic contributions; but within any society genetic variation has a substantial influence on individual risk. The genes presently known to affect alcohol dependence produce variation in alcoho...
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Received: 26 November 10 Accepted: 18 January 11 Published: 21 February 11 Surg Neurol Int 2011, 2:19 This article is available from: http://www.surgicalneurologyint.com/content/1/2/19 Copyright: © 2011 Hilton DL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
متن کاملTheoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder.
Alcoholism can be defined by a compulsion to seek and take drug, loss of control in limiting intake, and the emergence of a negative emotional state when access to the drug is prevented. Alcoholism impacts multiple motivational mechanisms and can be conceptualized as a disorder that includes a progression from impulsivity (positive reinforcement) to compulsivity (negative reinforcement). The co...
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ژورنال
عنوان ژورنال: Current Medicinal Chemistry
سال: 2015
ISSN: 0929-8673
DOI: 10.2174/0929867321666141229103158